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Fernando Vinuela, MD
  

Selected Publications

Selected Publications

1. Kidwell CS, Latour L, Saver JL, Alger JR, Starkman S, Duckwiler G, Jahan R, Vinuela F, Kang DW, Warach S. Thrombolytic Toxicity: Blood Brain Barrier Disruption in Human Ischemic Stroke. Cerebrovasc Dis. 25(4):338-343 (2008).

2. Loh Y, McArthur DL, Tateshima S, Jahan R, Duckwiler GR, Vinuela F. Safety of intracranial endovascular aneurysm therapy using 3-dimensional rotational angiography: a single-center experience. Surg Neurol. 69(2):158-63; discussion (2008).

3. Jahan R, Stewart D, Vinters HV, Yong W, Vinuela F, Vandeberg P, Marder VJ. Middle Cerebral Artery Occlusion in the Rabbit Using Selective Angiography. Application for Assessment of Thrombolysis. Stroke. 2008 Mar 13; (2008).

4. Loh Y, Vespa PM, Vinuela F. Focal meningoencephalitis and mycotic aneurysms from suspected aneurysm coil seeding. Neurology. 69(6):613 (2007).

5. Bang OY, Buck BH, Saver JL, Alger JR, Yoon SR, Starkman S, Ovbiagele B, Kim D, Ali LK, Sanossian N, Jahan R, Duckwiler GR, Vinuela F, Salamon N, Villablanca JP, Liebeskind DS. Prediction of hemorrhagic transformation after recanalization therapy using T2*-permeability magnetic resonance imaging. Ann Neurol. 2007 Aug 7; (2007).

6. Yuki I, Lee D, Murayama Y, Chiang A, Vinters HV, Nismmura I, Wang CJ, Ishii A, Wu BM, Vinuela F. Thrombus organization and healing in an experimental aneurysm model. Part II. The effect of various types of bioactive bioabsorbable polymeric coils. J Neurosurg. 107(1):109-20 (2007).

7. Lee D, Yuki I, Murayama Y, Chiang A, Nishimura I, Vinters HV, Wang CJ, Nien YL, Ishil A, Wu BM, Vinuela F. Thrombus organization and healing in the swine experimental aneurysm model. Part I. A histological and molecular analysis. J Neurosurg. 107(1):94-108 (2007).

8. Jahan R, Solberg TD, Lee D, Medin P, Tateshima S, De Salles A, Sayre J, Vinters HV, Vinuela F. An arteriovenous malformation model for stereotactic radiosurgery research. Neurosurgery. 61(1):152-9; discussion 1 (2007).

9. Venugopal P, Valentino D, Schmitt H, Villablanca JP, Vinuela F, Duckwiler G. Sensitivity of patient-specific numerical simulation of cerebal aneurysm hemodynamics to inflow boundary conditions. J Neurosurg. 106(6):1051-60 (2007).

10. Ahn S, Shin D, Tateshima S, Tanishita K, Vinuela F, Sinha S. Fluid-induced wall shear stress in anthropomorphic brain aneurysm models: MR phase-contrast study at 3 T. J Magn Reson Imaging. 25(6):1120-30 (2007).

11. Gonzalez NR, Boscardin WJ, Glenn T, Vinuela F, Martin NA. Vasospasm probability index: a combination of transcranial doppler velocities, cerebral blood flow, and clinical risk factors to predict cerebral vasospasm after aneurysmal subarachnoid hemorrhage. J Neurosurg. 107(6):1101-12 (2007).

12. Bang OY, Saver JL, Buck BH, Alger JR, Starkman S, Ovbiagele B, Kim D, Jahan R, Duckwiler GR, Yoon SR, Vinuela F, Liebeskind DS. Impact of collateral flow on tissue fate in acute ischemic stroke. J Neurol Neurosurg Psychiatry. 2007 Dec 20; (2007).

13. Guglielmi G, Vinuela F, Guidetti G, Dazzi M. The Guglielmi detachable coil "crescent" in the endovascular treatment of peripheral brain aneurysms: technical case report. Neurosurgery. 61(5 Suppl 2):E295-6; dis (2007).

14. Grinstead JW, Sinha S, Tateshima S, Nien YL, Vinuela F. Visualization and Quantification of Flow and Velocity Fields in Intracranial Arteriovenous Malformations Using Phase-Contrast MR Angiography. AJR Am J Roentgenol. 186(2):553-5 (2006).

15. Gonzalez NR, Duckwiler G, Jahan R, Murayama Y, Vinuela F. Challenges in the Endovascular Treatment of Giant Intracranial Aneurysms. Neurosurgery. 59(5 SUPPL 3):S113-S124 (2006).

16. Upchurch K, Feng L, Duckwiler GR, Frazee JG, Martin NA, Vinuela F. Nongalenic arteriovenous fistulas: history of treatment and technology. Neurosurg Focus. 20(6):E8 (2006).

17. Marder VJ, Chute DJ, Starkman S, Abolian AM, Kidwell C, Liebeskind D, Ovbiagele B, Vinuela F, Duckwiler G, Jahan R, Vespa PM, Selco S, Rajajee V, Kim D, Sanossian N, Saver JL. Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke. Stroke. 37(8):2086-93 (2006).

18. Marder VJ, Chute DJ, Starkman S, Abolian AM, Kidwell C, Liebeskind D, Ovbiagele B, Vinuela F, Duckwiler G, Jahan R, Vespa PM, Selco S, Rajajee V, Kim D, Sanossian N, Saver JL. Analysis of Thrombi Retrieved From Cerebral Arteries of Patients With Acute Ischemic Stroke. Stroke. 2006 Jun 22; (2006).

19. Grinstead JW, Sinha S, Tateshima S, Nien YL, Vinuela F. Visualization and quantification of flow and velocity fields in intracranial arteriovenous malformations using phase-contrast MR angiography. AJR Am J Roentgenol. 186(2):553-5 (2006).

20. Jahan R, Solberg TD, Lee D, Medin P, Tateshima S, Sayre J, De Salles A, Vinters HV, Vinuela F. Stereotactic radiosurgery of the rete mirabile in swine: a longitudinal study of histopathological changes. Neurosurgery. 58(3):551-8; discussion 5 (2006).

21. Murayama Y, Vinuela F, Ishii A, Nien YL, Yuki I, Duckwiler G, Jahan R. Initial clinical experience with matrix detachable coils for the treatment of intracranial aneurysms. J Neurosurg. 105(2):192-9 (2006).

22. Suzuki S, Jahan R, Duckwiler GR, Frazee J, Martin N, Vinuela F. Contribution of endovascular therapy to the management of poor-grade aneurysmal subarachnoid hemorrhage: Clinical and angiographic outcomes. J Neurosurg. 105(5):664-70 (2006).

23. Gonzalez NR, Duckwiler G, Jahan R, Murayama Y, Vinuela F. Challenges in the endovascular treatment of giant intracranial aneurysms. Neurosurgery. 59(5 Suppl 3):S113-24; di (2006).

24. Villablanca JP, Achiriolaie A, Hooshi P, Martin N, Duckwiler G, Jahan R, Frazee J, Gobin P, Sayre J, Vinuela F. Aneurysms of the posterior circulation: detection and treatment planning using volume-rendered three-dimensional helical computerized tomography angiography. J Neurosurg. 103(6):1018-29 (2005).

25. Gonzalez NR, Patel AB, Murayama Y, Vinuela F. Angiographic evidence of aneurysm neck healing following endovascular treatment with bioactive coils. AJNR Am J Neuroradiol. 26(4):912-4 (2005).

26. Yuki I, Murayama Y, Vinuela F. Development of medical devices for neuro-interventional procedures: special focus on aneurysm treatment. Expert Rev Med Devices. 2(5):539-46 (2005).

27. Yuki I, Murayama Y, Vinuela F. Endovascular management of dissecting vertebrobasilar artery aneurysms in patients presenting with acute subarachnoid hemorrhage. J Neurosurg. 103(4):649-55 (2005).

28. Moret J, Vinuela F. We thank Drs Sluzewski and van Rooij for their critcisms of the ACTIVE Study. AJNR Am J Neuroradiol. 26(8):2163 (2005).

29. Suzuki S, Kidwell CS, Starkman S, Saver JL, Duckwiler G, Vinuela F, Ovbiagele B. Use of multimodal MRI and novel endovascular therapies in a patient ineligible for intravenous tissue plasminogen activator. Stroke. 36(9):e77-9 (2005).

30. Feng L, Vinuela F, Murayama Y. Healing of intracranial aneurysms with bioactive coils. Neurosurg Clin N Am. 16(3):487-99, v-vi (2005).

31. Tateshima S, Grinstead J, Sinha S, Nien YL, Murayama Y, Villablanca JP, Tanishita K, Vinuela F. Intraaneurysmal flow visualization by using phase-contrast magnetic resonance imaging: feasibility study based on a geometrically realistic in vitro aneurysm model. J Neurosurg. 100(6):1041-8 (2004).

32. Gobin YP, Starkman S, Duckwiler GR, Grobelny T, Kidwell CS, Jahan R, Pile-Spellman J, Segal A, Vinuela F, Saver JL. MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia. Stroke. 35(12):2848-54 (2004).

33. Gonzalez N, Murayama Y, Nien YL, Martin N, Frazee J, Duckwiler G, Jahan R, Gobin YP, Vinuela F. Treatment of unruptured aneurysms with GDCs: clinical experience with 247 aneurysms. AJNR Am J Neuroradiol. 25(4):577-83 (2004).

34. Ostrem JL, Saver JL, Alger JR, Starkman S, Leary MC, Duckwiler G, Jahan R, Vespa P, Villablanca JP, Gobin YP, Vinuela F, Kidwell CS. Acute basilar artery occlusion: diffusion-perfusion MRI characterization of tissue salvage in patients receiving intra-arterial stroke therapies. Stroke. 35(2):e30-4 (2004).

35. Leary MC, Kidwell CS, Villablanca JP, Starkman S, Jahan R, Duckwiler GR, Gobin YP, Sykes S, Gough KJ, Ferguson K, Llanes JN, Masamed R, Tremwel M, Ovbiagele B, Vespa PM, Vinuela F, Saver JL. Validation of computed tomographic middle cerebral artery "dot"sign: an angiographic correlation study. Stroke. 34(11):2636-40 (2003).

36. Tateshima S, Vinuela F, Villablanca JP, Murayama Y, Morino T, Nomura K, Tanishita K. Three-dimensional blood flow analysis in a wide-necked internal carotid artery-ophthalmic artery aneurysm. J Neurosurg. 99(3):526-33 (2003).

37. Murayama Y, Tateshima S, Gonzalez NR, Vinuela F. Matrix and bioabsorbable polymeric coils accelerate healing of intracranial aneurysms: long-term experimental study. Stroke. 34(8):2031-7 (2003).

38. Shih LC, Saver JL, Alger JR, Starkman S, Leary MC, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Villablanca JP, Vespa PM, Kidwell CS. Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue. Stroke. 34(6):1425-30 (2003).

39. Murayama Y, Nien YL, Duckwiler G, Gobin YP, Jahan R, Frazee J, Martin N, Vinuela F. Guglielmi detachable coil embolization of cerebral aneurysms: 11 years' experience. J Neurosurg. 98(5):959-66 (2003).

40. Jahan R, Vinuela F. Intraarterial thrombolysis for acute ischemic stroke. Adv Neurol. 92:383-7 (2003).

41. Leary MC, Saver JL, Gobin YP, Jahan R, Duckwiler GR, Vinuela F, Kidwell CS, Frazee J, Starkman S. Beyond tissue plasminogen activator: mechanical intervention in acute stroke. Ann Emerg Med. 41(6):838-46 (2003).

42. Murayama Y, Song JK, Uda K, Gobin YP, Duckwiler GR, Tateshima S, Patel AB, Martin NA, Vinuela F. Combined endovascular treatment for both intracranial aneurysm and symptomatic vasospasm. AJNR Am J Neuroradiol. 24(1):133-9 (2003).

43. Tateshima S, Murayama Y, Villablanca JP, Morino T, Nomura K, Tanishita K, Vinuela F. In vitro measurement of fluid-induced wall shear stress in unruptured cerebral aneurysms harboring blebs. Stroke. 34(1):187-92 (2003).

44. Kidwell CS, Saver JL, Villablanca JP, Duckwiler G, Fredieu A, Gough K, Leary MC, Starkman S, Gobin YP, Jahan R, Vespa P, Liebeskind DS, Alger JR, Vinuela F. Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke. 33(1):95-8 (2002).

45. Kidwell CS, Saver JL, Carneado J, Sayre J, Starkman S, Duckwiler G, Gobin YP, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Vinuela F. Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis. Stroke. 33(3):717-24 (2002).

46. Alexander MJ, Duckwiler GR, Gobin YP, Vinuela F. Management of intraprocedural arterial thrombus in cerebral aneurysm embolization with abciximab: technical case report. Neurosurgery. 50(4):899-901; discussion (2002).

47. Murayama Y, Vinuela F, Tateshima S, Gonzalez NR, Song JK, Mahdavieh H, Iruela-Arispe L. Cellular responses of bioabsorbable polymeric material and Guglielmi detachable coil in experimental aneurysms. Stroke. 33(4):1120-8 (2002).

48. Song JK, Patel AB, Duckwiler GR, Gobin YP, Jahan R, Martin NA, Cacayorin ED, Vinuela F. Adult pial arteriovenous fistula and superior sagittal sinus stenosis: angiographic evidence for high-flow venopathy at an atypical location. Case report. J Neurosurg. 96(4):792-5 (2002).

49. Villablanca JP, Hooshi P, Martin N, Jahan R, Duckwiler G, Lim S, Frazee J, Gobin YP, Sayre J, Bentson J, Vinuela F. Three-dimensional helical computerized tomography angiography in the diagnosis, characterization, and management of middle cerebral artery aneurysms: comparison with conventional angiography and intraoperative findings. J Neurosurg. 97(6):1322-32 (2002).

50. Kidwell CS, Saver JL, Starkman S, Duckwiler G, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Gobin YP, Vinuela F, Alger JR. Late secondary ischemic injury in patients receiving intraarterial thrombolysis. Ann Neurol. 52(6):698-703 (2002).

51. Johnston SC, Higashida RT, Barrow DL, Caplan LR, Dion JE, Hademenos G, Hopkins LN, Molyneux A, Rosenwasser RH, Vinuela F, Wilson CB. Recommendations for the endovascular treatment of intracranial aneurysms: a statement for healthcare professionals from the Committee on Cerebrovascular Imaging of the American Heart Association Council on Cardiovascular Radiology. Stroke. 33(10):2536-44 (2002).

52. Villablanca JP, Jahan R, Hooshi P, Lim S, Duckwiler G, Patel A, Sayre J, Martin N, Frazee J, Bentson J, Vinuela F. Detection and characterization of very small cerebral aneurysms by using 2D and 3D helical CT angiography. AJNR Am J Neuroradiol. 23(7):1187-98 (2002).

53. Oskouian RJ Jr, Martin NA, Lee JH, Glenn TC, Guthrie D, Gonzalez NR, Afari A, Vinuela F. Multimodal quantitation of the effects of endovascular therapy for vasospasm on cerebral blood flow, transcranial doppler ultrasonographic velocities, and cerebral artery diameters. Neurosurgery. 51(1):30-41; discussion 4 (2002).

54. Kidwell CS, Saver JL, Mattiello J, Warach S, Liebeskind DS, Starkman S, Vespa P, Vinuela F, Villablanca JP, Martin NA, Frazee J, Alger JR. Diffusion-perfusion MR evaluation of perihematomal injury in hyperacute intracerebral hemorrhage. Neurology. 57:1611-1617. (2001).

55. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Woods RP, Alger JR. Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans. Neurology. 57:2015-2021 (2001).

56. Kidwell CS, Saver JL, Villablanca JP, Duckwiler G, Fredieu A, Gough K, Leary MC, Starkman S, Gobin YP, Jahan R, Vespa P, Liebeskind DS, Alger JR, Vinuela F. MRI detection of microbleeds prior to thrombolysis: an emerging application. Stroke. 33:95-98 (2001).

57. Kidwell CS, Saver JL, Mattiello J, Warach S, Liebeskind DS, Starkman S, Vespa P, Vinuela F, Villablanca JP, Martin NA, Frazee J, Alger JR. Diffusion-perfusion MR evaluation of perihematomal injury in hyperacute intracerebral hemorrhage. Neurology. 57:1611-1617 (2001).

58. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Woods RP, Alger JR. Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans. Neurology. 57:2015-2021 (2001).

59. Villablanca JP, Jahan R, Hooshi P, Lim S, Duckwiler G, Patel A, Sayre J, Martin N, Frazee J, Bentson J, Vinuela F. Very small aneurysms: detection and characterization using 2D and 3D helical CTA. AJNR. (2001).

60. Tateshima S, Murayama Y, Villablanca JP, Morino T, Takahashi H, Yamaguchi T, Tanishta K, Vinuela F. Intraaneurysmal flow dynamics study featuring an acrylic aneurysm model manufactured using a computerized tomography angiogram as a mold. J Neurosurgery. 95:1020-1027 (2001).

61. Jahan R, Murayama Y, Gobin YP, Duckwiler GR, Vinters HV, Vinuela F. Embolization of arteriovenous malformations with Onyx: Clinicopathologic experience in 23 patients. Neurosurgery. 48:984-997 (2001).

62. Song JK, Gobin YP, Duckwiler GR, Murayama Y, Frazee JG, Martin NA, Vinuela F. NBCA embolization of spinal dural arteriovenous fistulae: Technical results and clinical outcome. AJNR. 22: 40-47 (2001).

63. Vinuela F, Murayama Y, Duckwiler GR, Gobin YP. Present and future technical developments on aneurysm embolization. Impact on indications and anatomic results. Clin Neurosurg. 47:221-41 (2001).

64. Vinuela F, Murayama Y, Duckwiler GM, Gobin YP, Jahan R. The "unreachable" peaks of the neurointerventional mountaineers. Neurosurgery. 698-9 (2001).

65. Murayama Y, Vinuela F, Tateshima S, Song JK, Gonzalez N, Wallace MP. Bio-absorbable polymeric material (BPM) coils for embolization of intracranial aneurysms: Preliminary experimental study. J Neurosurg. 454-463 (2001).

66. Song JK, Vinuela F, Gobin YP, Duckwiler GR, Murayama Y, Kureshi I, Frazee JG, Martin NA. Surgical and endovascular treatment of spinal dural arteriovenous fistulas: long-term disability assessment and prognostic factors. J Neurosurg. 94:199-204 (2001).

67. Uda K, Murayama Y, Gobin YP, Duckwiler GR, Vinuela F. Endovascular treatment of basilar trunk aneurysms using GDC technology. J Neurosurg. 95:624-632 (2001).

68. Tateshima S, Murayama Y, Villablanca JP, Morino T, Takahashi H, Yamauchi T, Tanishita K, Vinuela F. Intraaneurysmal flow dynamics study featuring an acrylic aneurysm model manufactured using a computerized tomography angiogram as a mold. J Neurosurg. 95:1020-7 (2001).

69. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Kalafut M, Alger JR. Thrombolytic Reversal of Acute Human Cerebral Ischemic Injury shown by Diffusion/Perfusion Magnetic Resonance Imaging. Annals of Neurology. 47:462-9 (2000).

70. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin P, Jahan R, Vespa P, Kalafut M, Alger JR. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Annals of Neurology. 47:462-469 (2000).

71. Chow K, Gobin YP, Saver JL, Kidwell CS, Dong P, Vinuela F. Endovascular treatment of dural sinus thrombosis with rheolytic thrombectomy and intra-arterial thrombolysis. Stroke. 31:1420-1425 (2000).

72. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin P, Jahan R Vespa P, Kalafut M, Alger JR. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Annals of Neurology. 47:462-469 (2000).

73. Chow K, Gobin VP, Saver J, Kidwell C, Dong P, Vinuela F. Endovascular treatment of dural sinus thrombosis with rheolytic thrombectorny and intra-arterlat thrombolysis. Stroke. 31:1420-1425 (2000).

74. Villablanca JP, Martin N, Jahan R, Gobin YP, Frazee J, Duckwiler G, Bentson J, Hardart M, Coiteiro D, Sayre j, Vinuela F. Volume rendered helical computerized tomography angiography in the detection and characterization of intracranial aneurysms. J Neurosurg. 93(2):254-264 (2000).

75. Chow KL, Gobin YP, Cloughesy T, Sayre JW, Villablanca JP, Vinuela F. Prognostic factors in recurrent glioblastoma multiforme and anaplastic astrocytoma treated with selective intra-arterial chemotherapy. AJNR Am J Neuroradiol. 21(3):471-478 (2000).





















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