Jeffrey L. Saver, MD | UCLA Stroke Center

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Jeffrey L. Saver, MD

	Home Page
	Biography
	Selected Publications
	Honors and Awards

Homepage

Clinical Specialty

Stroke and Vascular Neurology

Behavioral Neurology and Neuropsychiatry

Research Interest

Thrombolytic stroke therapy

UCLA Stroke Center: www.stroke.ucla.edu

Neuroprotective stroke therapy

Stroke prevention

Novel stroke diagnostic methods

Vascular dementia

Neural substrates of language, memory, executive function, visuospatial function, and hemineglect

Neuropsychiatry

Educational Background

Post Graduate

1991-1992 Brown University / Rhode Island Hospital Providence, Rhode Island

Fellow in Cerebrovascular Disorders

Department of Neurology

1990-1991 University of Iowa

Iowa City, Iowa

Fellow in Behavioral Neurology and Cognitive Neuroscience

Department of Neurology

1989-1990 Harvard Longwood Neurology Training Program

Boston, Massachusetts

Chief Resident, Neurology

1987-1990 Harvard Longwood Neurology Training Program

Boston, Massachusetts

Neurology Residency

1986-1987 Brigham & Women's Hospital

Boston, Massachusetts

Medical Internship

Medical

1982-1986 Harvard Medical School

Boston, Massachusetts

M.D., 1986

Undergraduate

1977-1981 Harvard Medical School

Boston, Massachusetts

A.B., 1981

Selected Publications

1. Ovbiagele B, Buck BH, Liebeskind DS, Starkman S, Bang OY, Ali LK, Villablanca JP, Salamon N, Yun SW, Pineda S, Saver JL. Prior antiplatelet use and infarct volume in ischemic stroke. J Neurol Sci. 264(1-2):140-4 (2008).

2. Rahiman A, Saver JL, Porter V, Buxton W, McNair N, Razinia T, Ovbiagele B. In-hospital initiation of secondary prevention is associated with improved vascular outcomes at 3 months. J Stroke Cerebrovasc Dis. 17(1):5-8 (2008).

3. Rajajee V, Kidwell C, Starkman S, Ovbiagele B, Alger J, Villablanca P, Saver JL. Diagnosis of lacunar infarcts within 6 hours of onset by clinical and CT criteria versus MRI. J Neuroimaging. 18(1):66-72 (2008).

4. Buck BH, Liebeskind DS, Saver JL, Bang OY, Yun SW, Starkman S, Ali LK, Kim D, Villablanca JP, Salamon N, Razinia T, Ovbiagele B. Early neutrophilia is associated with volume of ischemic tissue in acute stroke. Stroke. 39(2):355-60 (2008).

5. Kidwell CS, Latour L, Saver JL, Alger JR, Starkman S, Duckwiler G, Jahan R, Vinuela F, Kang DW, Warach S. Thrombolytic Toxicity: Blood Brain Barrier Disruption in Human Ischemic Stroke. Cerebrovasc Dis. 25(4):338-343 (2008).

6. Smith WS, Sung G, Saver J, Budzik R, Duckwiler G, Liebeskind DS, Lutsep HL, Rymer MM, Higashida RT, Starkman S, Gobin YP. Mechanical Thrombectomy for Acute Ischemic Stroke. Final Results of the Multi MERCI Trial. Stroke. 2008 Feb 28; (2008).

7. Sanossian N, Saver JL, Navab M, Ovbiagele B. High-density lipoprotein cholesterol: an emerging target for stroke treatment. Stroke. 38(3):1104-9 (2007).

8. Saver JL. Deriving number-needed-to-treat and number-needed-to-harm from the SAINT I trial results. Stroke. 38(2):257; author reply 2 (2007).

9. Acker JE 3rd, Pancioli AM, Crocco TJ, Eckstein MK, Jauch EC, Larrabee H, Meltzer NM, Mergendahl WC, Munn JW, Prentiss SM, Sand C, Saver JL, Eigel B, Gilpin BR, Schoeberl M, Solis P, Bailey JR, Horton KB, Stranne SK. Implementation strategies for emergency medical services within stroke systems of care: a policy statement from the American Heart Association/American Stroke Association Expert Panel on Emergency Medical Services Systems and the Stroke Council. Stroke. 38(11):3097-115 (2007).

10. Buck BH, Liebeskind DS, Saver JL, Bang OY, Starkman S, Ali LK, Kim D, Villablanca JP, Salamon N, Yun SW, Razinia T, Ovbiagele B. Association of higher serum calcium levels with smaller infarct volumes in acute ischemic stroke. Arch Neurol. 64(9):1287-91 (2007).

11. Saver JL. Intra-Arterial Fibrinolysis for Acute Ischemic Stroke. The Message of Melt. Stroke. 2007 Aug 16; (2007).

12. Bang OY, Buck BH, Saver JL, Alger JR, Yoon SR, Starkman S, Ovbiagele B, Kim D, Ali LK, Sanossian N, Jahan R, Duckwiler GR, Vinuela F, Salamon N, Villablanca JP, Liebeskind DS. Prediction of hemorrhagic transformation after recanalization therapy using T2*-permeability magnetic resonance imaging. Ann Neurol. 2007 Aug 7; (2007).

13. Buck BH, Saver JL. A case of acute ischemic stroke: optimizing management with penumbra and vessel imaging. Nat Clin Pract Neurol. 3(8):465-9 (2007).

14. Saver JL, Yafeh B. Confirmation of tPA treatment effect by baseline severity-adjusted end point reanalysis of the NINDS-tPA stroke trials. Stroke. 38(2):414-6 (2007).

15. Ovbiagele B, Lynn MJ, Saver JL, Chimowitz MI. Leukocyte count and vascular risk in symptomatic intracranial atherosclerosis. Cerebrovasc Dis. 24(2-3):283-8 (2007).

16. Saver JL. Hemorrhage after thrombolytic therapy for stroke: the clinically relevant number needed to harm. Stroke. 38(8):2279-83 (2007).

17. Ali LK, Saver JL. The ischemic stroke patient who worsens: new assessment and management approaches. Rev Neurol Dis. 4(2):85-91 (2007).

18. Sanossian N, Ances BM, Shah SH, Kim D, Saver JL, Liebeskind DS. FLAIR vascular hyperintensity may predict stroke after TIA. Clin Neurol Neurosurg. 109(7):617-9 (2007).

19. Saver JL, Yafeh B. Confirmation of tPA Treatment Effect by Baseline Severity-Adjusted End Point Reanalysis of the NINDS-tPA Stroke Trials. Stroke. 2007 Jan 18; (2007).

20. Towfighi A, Saver JL, Engelhardt R, Ovbiagele B. A midlife stroke surge among women in the United States. Neurology. 2007 Jun 20; (2007).

21. Viehman JA, Saver JL, Liebeskind DS, Starkman S, Ali LK, Buck B, Razinia T, Ovbiagele B. Utility of urinalysis in discriminating cardioembolic stroke mechanism. Arch Neurol. 64(5):667-70 (2007).

22. Ovbiagele B, Saver JL. Intensive statin therapy after stroke or transient ischemic attack: a SPARCLing success?. Stroke. 38(3):1110-2 (2007).

23. Saver JL. Food and Drug Administration public hearing on the conduct of emergency clinical research: testimony of the American Stroke Association. Acad Emerg Med. 14(4):e57-8 (2007).

24. Saver JL. Clinical impact of NXY-059 demonstrated in the SAINT I trial: derivation of number needed to treat for benefit over entire range of functional disability. Stroke. 38(5):1515-8 (2007).

25. Razinia T, Saver JL, Liebeskind DS, Ali LK, Buck B, Ovbiagele B. Body mass index and hospital discharge outcomes after ischemic stroke. Arch Neurol. 64(3):388-91 (2007).

26. Saver JL. Food and Drug Administration Public Hearing on the Conduct of Emergency Clinical Research: Testimony of the American Stroke Association. Acad Emerg Med. 2007 Feb 25; (2007).

27. Rha JH, Saver JL. The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke. 38(3):967-73 (2007).

28. Ovbiagele B, Saver JL. Intensive statin therapy after stroke or transient ischemic attack: a sparcling success?. Stroke. 38(3):1110-2 (2007).

29. Saver JL. Intra-arterial fibrinolysis for acute ischemic stroke: the message of melt. Stroke. 38(10):2627-8 (2007).

30. Saver JL. Clinical trial registries. JAMA. 298(13):1514; author repl (2007).

31. Saver JL. Novel end point analytic techniques and interpreting shifts across the entire range of outcome scales in acute stroke trials. Stroke. 38(11):3055-62 (2007).

32. Ovbiagele B, Buck BH, Liebeskind DS, Starkman S, Bang OY, Ali LK, Villablanca JP, Salamon N, Yun SW, Pineda S, Saver JL. Prior antiplatelet use and infarct volume in ischemic stroke. J Neurol Sci. 2007 Sep 11; (2007).

33. Bang OY, Saver JL, Buck BH, Alger JR, Starkman S, Ovbiagele B, Kim D, Jahan R, Duckwiler GR, Yoon SR, Vinuela F, Liebeskind DS. Impact of collateral flow on tissue fate in acute ischemic stroke. J Neurol Neurosurg Psychiatry. 2007 Dec 20; (2007).

34. Buck BH, Liebeskind DS, Saver JL, Bang OY, Yun SW, Starkman S, Ali LK, Kim D, Villablanca JP, Salamon N, Razinia T, Ovbiagele B. Early Neutrophilia Is Associated With Volume of Ischemic Tissue in Acute Stroke. Stroke. 2007 Dec 27; (2007).

35. Saver JL. Cryptogenic stroke in patients with patent foramen ovale. Curr Atheroscler Rep. 9(4):319-25 (2007).

36. Ovbiagele B, Weir CJ, Saver JL, Muir KW, Lees KR. Effect of Smoking Status on Outcome after Acute Ischemic Stroke. Cerebrovasc Dis. 21(4):260-265 (2006).

37. Saver JL. Optimizing an evidence-based causative classification system for ischemic stroke. Ann Neurol. 59(2):434 (2006).

38. Ovbiagele B, Saver JL. Ensuring management of vascular risk factors after stroke. Rev Neurol Dis. 3(3):93-100 (2006).

39. Sanossian N, Saver JL, Ovbiagele B. Aspirin and stroke severity. Stroke. 37(11):2660; author reply (2006).

40. Goldstein LB, Saver JL. Thrombolysis in stroke: a medicolegal quagmire. Stroke. 37(11):2663; author reply (2006).

41. Goldstein LB, Saver JL. Thrombolysis in Stroke: a Medicolegal Quagmire. Stroke. 2006 Sep 21; (2006).

42. Sanossian N, Ohanian AG, Saver JL, Kim LI, Ovbiagele B. Frequency and determinants of nonpublication of research in the stroke literature. Stroke. 37(10):2588-92 (2006).

43. Sanossian N, Saver JL, Ovbiagele B. Aspirin and Stroke Severity. Stroke. 2006 Sep 14; (2006).

44. Saver JL. Can acute MRI predict outcome following transient ischemic attack and minor stroke?. Nat Clin Pract Neurol. 2(1):14-5 (2006).

45. Neumann-Haefelin T, Hoelig S, Berkefeld J, Fiehler J, Gass A, Humpich M, Kastrup A, Kucinski T, Lecei O, Liebeskind DS, Rother J, Rosso C, Samson Y, Saver JL, Yan B. Leukoaraiosis Is a Risk Factor for Symptomatic Intracerebral Hemorrhage After Thrombolysis for Acute Stroke. Stroke. 2006 Aug 24; (2006).

46. Sanossian N, Ohanian AG, Saver JL, Kim LI, Ovbiagele B. Frequency and Determinants of Nonpublication of Research in the Stroke Literature. Stroke. 2006 Aug 24; (2006).

47. Sanossian N, Saver JL, Liebeskind DS, Kim D, Razinia T, Ovbiagele B. Achieving target cholesterol goals after stroke: is in-hospital statin initiation the key?. Arch Neurol. 63(8):1081-3 (2006).

48. Ovbiagele B, Saver JL, Sanossian N, Salamon N, Villablanca P, Alger JR, Razinia T, Kim D, Liebeskind DS. Predictors of Cerebral Microbleeds in Acute Ischemic Stroke and TIA Patients. Cerebrovasc Dis. 22(5-6):378-383 (2006).

49. Ovbiagele B, Saver JL. Cerebral white matter hyperintensities on MRI: Current concepts and therapeutic implications. Cerebrovasc Dis. 22(2-3):83-90 (2006).

50. Saver JL, Goldstein LB. Response to Letter by Hart. Stroke. 2006 Jul 6; (2006).

51. Marder VJ, Chute DJ, Starkman S, Abolian AM, Kidwell C, Liebeskind D, Ovbiagele B, Vinuela F, Duckwiler G, Jahan R, Vespa PM, Selco S, Rajajee V, Kim D, Sanossian N, Saver JL. Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke. Stroke. 37(8):2086-93 (2006).

52. Saver JL. Does the Merci Retriever Work? For. Stroke. 2006 Apr 6; (2006).

53. Ovbiagele B, Saver JL, Lynn MJ, Chimowitz M. Impact of metabolic syndrome on prognosis of symptomatic intracranial atherostenosis. Neurology. 66(9):1344-9 (2006).

54. Ovbiagele B, Saver JL. Cerebral White Matter Hyperintensities on MRI: Current Concepts and Therapeutic Implications. Cerebrovasc Dis. 22(2-3):83-90 (2006).

55. Marder VJ, Chute DJ, Starkman S, Abolian AM, Kidwell C, Liebeskind D, Ovbiagele B, Vinuela F, Duckwiler G, Jahan R, Vespa PM, Selco S, Rajajee V, Kim D, Sanossian N, Saver JL. Analysis of Thrombi Retrieved From Cerebral Arteries of Patients With Acute Ischemic Stroke. Stroke. 2006 Jun 22; (2006).

56. Ovbiagele B, Hills NK, Saver JL, Johnston SC. Secondary-prevention drug prescription in the very elderly after ischemic stroke or TIA. Neurology. 66(3):313-8 (2006).

57. Saver JL, Goldstein LB. The new standing guideline committee policy of the american stroke association stroke council. Stroke. 37(3):753 (2006).

58. Saver JL, Goldstein LB. The new standing guideline committee policy of the American Stroke Association Stroke Council. Stroke. 37(3):753 (2006).

59. Ovbiagele B, Weir CJ, Saver JL, Muir KW, Lees KR. Effect of smoking status on outcome after acute ischemic stroke. Cerebrovasc Dis. 21(4):260-5 (2006).

60. Saver JL, Kidwell C, Eckstein M, Ovbiagele B, Starkman S. Physician-investigator phone elicitation of consent in the field: a novel method to obtain explicit informed consent for prehospital clinical research. Prehosp Emerg Care. 10(2):182-5 (2006).

61. Saver JL, Goldstein LB. The New Standing Guideline Committee Policy of the American Stroke Association Stroke Council. Stroke. 2006 Feb 2; (2006).

62. Ovbiagele B, Hills NK, Saver JL, Johnston SC. Lipid assessment and treatment patterns in hospitalized TIA and ischemic stroke patients. J Hosp Med. 1(4):214-20 (2006).

63. Saver JL. Time is brain--quantified. Stroke. 37(1):263-6 (2006).

64. Saver JL. Does the Merci Retriever work? For. Stroke. 37(5):1340-1; discussion (2006).

65. Liebeskind DS, Kidwell CS, Sayre JW, Saver JL. Evidence of publication bias in reporting acute stroke clinical trials. Neurology. 67(6):973-9 (2006).

66. Saver JL. Deriving Number-Needed-to-Treat and Number-Needed-to-Harm From the Saint I Trial Results. Stroke. 2006 Dec 21; (2006).

67. Neumann-Haefelin T, Hoelig S, Berkefeld J, Fiehler J, Gass A, Humpich M, Kastrup A, Kucinski T, Lecei O, Liebeskind DS, Rother J, Rosso C, Samson Y, Saver JL, Yan B. Leukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute stroke. Stroke. 37(10):2463-6 (2006).

68. Ovbiagele B, Saver JL, Sanossian N, Salamon N, Villablanca P, Alger JR, Razinia T, Kim D, Liebeskind DS. Predictors of cerebral microbleeds in acute ischemic stroke and TIA patients. Cerebrovasc Dis. 22(5-6):378-83 (2006).

69. Sanossian N, Saver JL, Kim D, Razinia T, Ovbiagele B. Do high-density lipoprotein cholesterol levels influence stroke severity?. J Stroke Cerebrovasc Dis. 15(5):187-9 (2006).

70. Ovbiagele B, Hills NK, Saver JL, Johnston SC. Frequency and determinants of pneumonia and urinary tract infection during stroke hospitalization. J Stroke Cerebrovasc Dis. 15(5):209-13 (2006).

71. Ovbiagele B, Hills NK, Saver JL, Johnston SC. Are racial differences in antihypertensive responsiveness reflected in usage after stroke?. J Stroke Cerebrovasc Dis. 15(6):260-5 (2006).

72. Bash S, Villablanca JP, Jahan R, Duckwiler G, Tillis M, Kidwell C, Saver J, Sayre J. Intracranial vascular stenosis and occlusive disease: evaluation with CT angiography, MR angiography, and digital subtraction angiography. AJNR Am J Neuroradiol. 26(5):1012-21 (2005).

73. Akopov SE, Suzuki S, Fredieu A, Kidwell CS, Saver JL, Cohen SN. Withdrawal of warfarin prior to a surgical procedure: time to follow the guidelines?. Cerebrovasc Dis. 19(5):337-42 (2005).

74. Ovbiagele B, Kidwell CS, Saver JL. Expanding indications for statins in cerebral ischemia: a quantitative study. Arch Neurol. 62(1):67-72 (2005).

75. Matsumoto J, Saver JL, Brennan KC, Ringman JM. Mitochondrial Encephalomyopathy With Lactic Acidosis and Stroke (MELAS). Rev Neurol Dis. 2(1):30-4 (2005).

76. Kim D, Saver JL. Patent foramen ovale and stroke: what we do and don't know. Rev Neurol Dis. 2(1):1-7 (2005).

77. Matsumoto J, Saver JL, Brennan KC, Ringman JM. Mitochondrial encephalomyopathy with lactic acidosis and stroke (MELAS). Rev Neurol Dis. 2(1):30-4 (2005).

78. Lai DW, Saver JL, Araujo JA, Reidl M, Tobis J. Pericarditis associated with nickel hypersensitivity to the Amplatzer occluder device: a case report. Catheter Cardiovasc Interv. 66(3):424-6 (2005).

79. Saver JL. Time Is Brain--Quantified. Stroke. 2005 Dec 8; (2005).

80. Ovbiagele B, Saver JL. Comments on 'when to measure lipid profile after stroke'. Cerebrovasc Dis. 20(3):211 (2005).

81. Ovbiagele B, Kidwell CS, Selco S, Razinia T, Saver JL. Treatment adherence rates one year after initiation of a systematic hospital-based stroke prevention program. Cerebrovasc Dis. 20(4):280-2 (2005).

82. Vespa P, McArthur D, Miller C, O'Phelan K, Frazee J, Kidwell C, Saver J, Starkman S, Martin N. Frameless stereotactic aspiration and thrombolysis of deep intracerebral hemorrhage is associated with reduction of hemorrhage volume and neurological improvement. Neurocrit Care. 2(3):274-81 (2005).

83. Molina CA, Saver JL. Extending reperfusion therapy for acute ischemic stroke: emerging pharmacological, mechanical, and imaging strategies. Stroke. 36(10):2311-20 (2005).

84. Rajajee V, Saver J. Prehospital care of the acute stroke patient. Tech Vasc Interv Radiol. 8(2):74-80 (2005).

85. Lai DW, Saver JL, Araujo JA, Reidl M, Tobis J. Pericarditis associated with nickel hypersensitivity to the Amplatzer occluder device: A case report. Catheter Cardiovasc Interv. 66(3):424-6 (2005).

86. Ovbiagele B, Saver JL. The smoking-thrombolysis paradox and acute ischemic stroke. Neurology. 65(2):293-5 (2005).

87. Ovbiagele B, Hills NK, Saver JL, Johnston SC. Antihypertensive medications prescribed at discharge after an acute ischemic cerebrovascular event. Stroke. 36(9):1944-7 (2005).

88. Suzuki S, Kidwell CS, Starkman S, Saver JL, Duckwiler G, Vinuela F, Ovbiagele B. Use of multimodal MRI and novel endovascular therapies in a patient ineligible for intravenous tissue plasminogen activator. Stroke. 36(9):e77-9 (2005).

89. Smith WS, Sung G, Starkman S, Saver JL, Kidwell CS, Gobin YP, Lutsep HL, Nesbit GM, Grobelny T, Rymer MM, Silverman IE, Higashida RT, Budzik RF, Marks MP. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke. 36(7):1432-8 (2005).

90. Suzuki S, Saver JL, Scott P, Jahan R, Duckwiler G, Starkman S, Su Y, Kidwell CS. Access to intra-arterial therapies for acute ischemic stroke: an analysis of the US population. AJNR Am J Neuroradiol. 25(10):1802-6 (2004).

91. Saver JL, Kidwell C, Eckstein M, Starkman S. Intravenous Magnesium for Neuroprotection in Acute Stroke: Neuropharmacology Supports Clinical Hope. Response. Stroke. 2004 Oct 28; (2004).

92. Saver JL. Number needed to treat estimates incorporating effects over the entire range of clinical outcomes: novel derivation method and application to thrombolytic therapy for acute stroke. Arch Neurol. 61(7):1066-70 (2004).

93. Kidwell CS, Alger JR, Saver JL. Evolving paradigms in neuroimaging of the ischemic penumbra. Stroke. 35(11 Suppl 1):2662-5 (2004).

94. Kidwell CS, Chalela JA, Saver JL, Starkman S, Hill MD, Demchuk AM, Butman JA, Patronas N, Alger JR, Latour LL, Luby ML, Baird AE, Leary MC, Tremwel M, Ovbiagele B, Fredieu A, Suzuki S, Villablanca JP, Davis S, Dunn B, Todd JW, Ezzeddi. Comparison of MRI and CT for detection of acute intracerebral hemorrhage. JAMA. 292(15):1823-30 (2004).

95. Gobin YP, Starkman S, Duckwiler GR, Grobelny T, Kidwell CS, Jahan R, Pile-Spellman J, Segal A, Vinuela F, Saver JL. MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia. Stroke. 35(12):2848-54 (2004).

96. Ovbiagele B, Saver JL, Fredieu A, Suzuki S, Selco S, Rajajee V, McNair N, Razinia T, Kidwell CS. In-hospital initiation of secondary stroke prevention therapies yields high rates of adherence at follow-up. Stroke. 35(12):2879-83 (2004).

97. Saver JL, Kidwell C. Neuroimaging in TIAs. Neurology. 62(8 Suppl 6):S22-5 (2004).

98. Saver JL, Kidwell C, Eckstein M, Starkman S. Prehospital neuroprotective therapy for acute stroke: results of the Field Administration of Stroke Therapy-Magnesium (FAST-MAG) pilot trial. Stroke. 35(5):e106-8 (2004).

99. Llanes JN, Kidwell CS, Starkman S, Leary MC, Eckstein M, Saver JL. The Los Angeles Motor Scale (LAMS): a new measure to characterize stroke severity in the field. Prehosp Emerg Care. 8(1):46-50 (2004).

100. Ostrem JL, Saver JL, Alger JR, Starkman S, Leary MC, Duckwiler G, Jahan R, Vespa P, Villablanca JP, Gobin YP, Vinuela F, Kidwell CS. Acute basilar artery occlusion: diffusion-perfusion MRI characterization of tissue salvage in patients receiving intra-arterial stroke therapies. Stroke. 35(2):e30-4 (2004).

101. Ferguson KN, Kidwell CS, Starkman S, Saver JL. Hyperacute treatment initiation in neuroprotective agent stroke trials. J Stroke Cerebrovasc Dis. 13(3):109-12 (2004).

102. Hanley D, Gorelick PB, Elliott WJ, Broder MS, Saver JL, Kidwell CS, Fagan SC, Wilson A, Lennihan L, Schwer WA, Rubenstein LZ, Crowell RM, Haines SJ, Lopez CC, Zorowitz R, Dubois RW. Determining the appropriateness of selected surgical and medical management options in recurrent stroke prevention: A guideline for primary care physicians from the National Stroke Association work group on recurrent stroke prevention. J Stroke Cerebrovasc Dis. 13(5):196-207 (2004).

103. Leary MC, Kidwell CS, Villablanca JP, Starkman S, Jahan R, Duckwiler GR, Gobin YP, Sykes S, Gough KJ, Ferguson K, Llanes JN, Masamed R, Tremwel M, Ovbiagele B, Vespa PM, Vinuela F, Saver JL. Validation of computed tomographic middle cerebral artery "dot"sign: an angiographic correlation study. Stroke. 34(11):2636-40 (2003).

104. Ovbiagele B, Kidwell CS, Starkman S, Saver JL. Potential Role of Neuroprotective Agents in the Treatment of Patients with Acute Ischemic Stroke. Curr Treat Options Cardiovasc Med. 5(6):441-449 (2003).

105. Kidwell CS, Alger JR, Saver JL. Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging. Stroke. 34(11):2729-35 (2003).

106. Leary MC, Saver JL. Annual incidence of first silent stroke in the United States: a preliminary estimate. Cerebrovasc Dis. 16(3):280-5 (2003).

107. Shih LC, Saver JL, Alger JR, Starkman S, Leary MC, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Villablanca JP, Vespa PM, Kidwell CS. Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue. Stroke. 34(6):1425-30 (2003).

108. Leary MC, Saver JL, Gobin YP, Jahan R, Duckwiler GR, Vinuela F, Kidwell CS, Frazee J, Starkman S. Beyond tissue plasminogen activator: mechanical intervention in acute stroke. Ann Emerg Med. 41(6):838-46 (2003).

109. Saver JL. A comparison of risk factors for recurrent TIA and stroke in patients diagnosed with TIA. Neurology. 60(11):1871; author reply (2003).

110. Ovbiagele B, Kidwell CS, Saver JL. Epidemiological impact in the United States of a tissue-based definition of transient ischemic attack. Stroke. 34(4):919-24 (2003).

111. Ovbiagele B, Kidwell CS, Starkman S, Saver JL. Neuroprotective agents for the treatment of acute ischemic stroke. Curr Neurol Neurosci Rep. 3(1):9-20 (2003).

112. Kidwell CS, Saver JL, Villablanca JP, Duckwiler G, Fredieu A, Gough K, Leary MC, Starkman S, Gobin YP, Jahan R, Vespa P, Liebeskind DS, Alger JR, Vinuela F. Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke. 33(1):95-8 (2002).

113. Kidwell CS, Saver JL, Carneado J, Sayre J, Starkman S, Duckwiler G, Gobin YP, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Vinuela F. Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis. Stroke. 33(3):717-24 (2002).

114. Kidwell CS, Saver JL, Starkman S, Duckwiler G, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Gobin YP, Vinuela F, Alger JR. Late secondary ischemic injury in patients receiving intraarterial thrombolysis. Ann Neurol. 52(6):698-703 (2002).

115. Albers GW, Caplan LR, Easton JD, Fayad PB, Mohr JP, Saver JL, Sherman DG. Transient ischemic attack--proposal for a new definition. N Engl J Med. 347(21):1713-6 (2002).

116. Kidwell CS, Saver JL, Mattiello J, Warach S, Liebeskind DS, Starkman S, Vespa P, Vinuela F, Villablanca JP, Martin NA, Frazee J, Alger JR. Diffusion-perfusion MR evaluation of perihematomal injury in hyperacute intracerebral hemorrhage. Neurology. 57:1611-1617. (2001).

117. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Woods RP, Alger JR. Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans. Neurology. 57:2015-2021 (2001).

118. Kidwell CS, Villablanca JP, Saver JL. Advances in neuroimaging of acute stroke. Current Atherosclerosis Reports. 2:126-135 (2001).

119. Kidwell CS, Liebeskind DS, Starkman S, Saver JL. Trends in ischemic stroke trials through the 20th century. Stroke. 32:1349-1359 (2001).

120. Kidwell CS, El-Saden S, Livshits S, Martin NA, Glenn TC, Saver JL. Transcranial Doppler pulsatility indices as a measure of diffuse small vessel disease. Journal of Neuroimaging. 11:229-235 (2001).

121. Kidwell CS, Saver JL, Villablanca JP, Duckwiler G, Fredieu A, Gough K, Leary MC, Starkman S, Gobin YP, Jahan R, Vespa P, Liebeskind DS, Alger JR, Vinuela F. MRI detection of microbleeds prior to thrombolysis: an emerging application. Stroke. 33:95-98 (2001).

122. Saver JL, Kidwell CS, Liebeskind DS, Starkman S. Acute ischemic stroke trials (Letter). Stroke. 32:275-8 (2001).

123. Chalela JA, Katzan I, Liebeskind DS, Rasmussen P, Zaidat O, Suarez JI, Chiu D, Klucznick RP, Jauch E, Cucchiara BL, Saver J, Kasner SE. Safety of intra-arterial thrombolysis in the postoperative period. Stroke. 32:1365-1369 (2001).

124. Worrall BB, Farace E, Hillis AE, Hutson RK, Wityk R, Saver JL, Johnston KC, Haley EC, RANTTAS Investigators. Correlation of aphasia and/or neglect with cortical infarction in a subpopulation of RANTTAS. Cerebrovascular Diseases. 11:257-264 (2001).

125. Saver JL, Kalafut M. Combination therapies and the theoretical limits of evidence-based medicine. Neuroepidemiology. 20:57-64 (2001).

126. Liebeskind DS, Buljubasic N, Saver JL. Cardioembolic stroke due to papillary fibroelastoma. Journal of Stroke and Cerebrovascular Diseases. 10:94-95 (2001).

127. Chalela JA, Katzan I, Liebeskind DS, Rasmussen P, Zaidat O, Suarez JI, Chiu D, Klucznick RP, Jauch E, Cucchiara BL, Saver JL, Kasner SE. Safety of intra-arterial thrombolysis in the postoperative period. Stroke. 32:1365-1369 (2001).

128. Saver JL. Intra-arterial thrombolysis. Neurology. 57 (2001).

129. Kidwell CS, Saver JL, Mattiello J, Warach S, Liebeskind DS, Starkman S, Vespa P, Vinuela F, Villablanca JP, Martin NA, Frazee J, Alger JR. Diffusion-perfusion MR evaluation of perihematomal injury in hyperacute intracerebral hemorrhage. Neurology. 57:1611-1617 (2001).

130. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Woods RP, Alger JR. Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans. Neurology. 57:2015-2021 (2001).

131. Kalafut MA, Saver JL. Thrombolytic therapy in stroke. Emedicine Neurology. (2001).

132. Kidwell CS, Saver JL, Mattielo J, Warach S, Liebeskind D, Starkman S, Vespa PM, Martin NA, Villablanca JP, Frazee J, Alger JR. Diffusion-perfusion MRI evaluation of perihematomal injury in hyperacute intracerebral hemorrhage. Neurology. 57:1611-1617 (2001).

133. Lee L, Kidwell C, Alger JR, Starkman S, Saver JL. Impact upon stroke subtype diagnosis of early diffusion weighted MRI and MR angiography. Stroke. 31:1081-1089 (2000).

134. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Kalafut M, Alger JR. Thrombolytic Reversal of Acute Human Cerebral Ischemic Injury shown by Diffusion/Perfusion Magnetic Resonance Imaging. Annals of Neurology. 47:462-9 (2000).

135. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin P, Jahan R, Vespa P, Kalafut M, Alger JR. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Annals of Neurology. 47:462-469 (2000).

136. Kidwell CS, Saver JL. Applications of multimodal MRI in patients receiving intra-arterial thrombolytic therapy. Stroke Clinical Updates. 10(3):1-4 (2000).

137. Kidwell CS, Martin NA, Saver JL. A new pocket-sized transcranial ultrasound device (NeuroDop): comparison with standard TCD. Journal of Neuroimaging. 10:91-95 (2000).

138. Kidwell CS, Saver JL, Starkman S. The acute stroke patient: prehospital stroke identification and treatment. In: Cohen SN, ed. Management of Ischemic Stroke. New York: McGraw-Hill. (2000).

139. Kidwell CS, Liebeskind DS, Saver JL. Diagnosis and management of central nervous system vasculitis. In: Cohen SN, ed Management of Ischemic Stroke. (2000).

140. Lee U, Kidwell CS, Alger JR, Starkman S, Saver JL. Impact on stroke subtype diagnosis of early diffusion-weighted magnetic resonance imaging and magnetic resonance angiography. Stroke. 31:1081-1089 (2000).

141. Kalafut MA, Gandhi R, Kidwell CS, Saver JL. Safety and cost of low-molecular-weight heparin as bridging anticoagulant therapy in subacute cerebral ischemia. Stroke. 31:2563-2568 (2000).

142. Chow K, Gobin YP, Saver JL, Kidwell CS, Dong P, Vinuela F. Endovascular treatment of dural sinus thrombosis with rheolytic thrombectomy and intra-arterial thrombolysis. Stroke. 31:1420-1425 (2000).

143. Kidwell CS, Villablanca JP, Saver JL. Advances in neuroimaging of acute stroke. Current Atherosclerosis Reports. 2:126-135 (2000).

144. Kidwell CS, Liebeskind DS, Saver JL. Central nervous system vasculitis. In: Cohen SN, ed. Management of Ischemic Stroke: A Clinical Approach. First ed. 329-358 (2000).

145. Kidwell CS, Saver JL, Starkman S. Prehospital emergency stroke care. In: Cohen SN, ed. Management of Ischemic Stroke: A Clinical Approach. First ed. 3-16 (2000).

146. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin P, Jahan R Vespa P, Kalafut M, Alger JR. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Annals of Neurology. 47:462-469 (2000).

147. Lee U, Kidwell, Alger JR, Starkman S, Saver JL. Impact on stroke subtype diagnosis of early diffusion-weighted magnetic resonance imaging and magnetic resonance angiography. Stroke. 31:1081-1089 (2000).

148. Chow K, Gobin VP, Saver J, Kidwell C, Dong P, Vinuela F. Endovascular treatment of dural sinus thrombosis with rheolytic thrombectorny and intra-arterlat thrombolysis. Stroke. 31:1420-1425 (2000).

149. Saver JL. Intra-arterial thrombolysis. Advances in Stroke Management Proceedings Highlights. 4:28-30 (2000).

150. Kalafut MA, Schriger DL, Saver JL, Starkman S. Detection of early CT signs of > 1/3 middle cerebral artery infarctions: interrater reliability and sensitivity of CT interpretation by physicians involved in acute stroke care. Stroke. 31:1667-1671 (2000).

151. Saver JL. Consultant.s Corner: A 68-year-old woman with a loud left carotid bruit. Family Practice Recertification. 22:11-20 (2000).

152. Kalafut MA, Saver JL. The acute stroke patient: the first lx hours. In: Cohen SN, ed. Management of Ischemic Stroke. New York: McGraw-Hill. (2000).

153. Kidwell CS, Starkman S, Eckstein M, Weems K, Saver JL. Identifying stroke in the field: prospective validation of the Los Angeles Prehospital Stroke Screen (LAPSS). Stroke. 31:71-76 (2000).

154. Saver JL. Peer exchange: secondary stroke prevention. Medical Crossfire. 2:30-31 (2000).

155. Saver JL. Commentary on: Trends in warfarin use to prevent stroke in atrial fibrillation. Cardiology Review. 17(10):17 (2000).

156. Kidwell CS, Villablanca JP, Saver JL. Advances in Neuroimaging of Acute stroke. Curr Atheroscler Rep. 2(2):126-135 (2000).

Featured Faculty

Bruce Dobkin, MD
Neurologic Rehabilitation Director & Stroke Neurology

August 2008

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