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Jeffrey R. Alger, PhD
Selected Publications 1. Rajajee V, Kidwell C, Starkman S, Ovbiagele B, Alger J, Villablanca P, Saver JL. Diagnosis of lacunar infarcts within 6 hours of onset by clinical and CT criteria versus MRI. J Neuroimaging. 18(1):66-72 (2008). 2. Kidwell CS, Latour L, Saver JL, Alger JR, Starkman S, Duckwiler G, Jahan R, Vinuela F, Kang DW, Warach S. Thrombolytic Toxicity: Blood Brain Barrier Disruption in Human Ischemic Stroke. Cerebrovasc Dis. 25(4):338-343 (2008). 3. Bang OY, Buck BH, Saver JL, Alger JR, Yoon SR, Starkman S, Ovbiagele B, Kim D, Ali LK, Sanossian N, Jahan R, Duckwiler GR, Vinuela F, Salamon N, Villablanca JP, Liebeskind DS. Prediction of hemorrhagic transformation after recanalization therapy using T2*-permeability magnetic resonance imaging. Ann Neurol. 2007 Aug 7; (2007). 4. Ford JM, Seiferheld W, Alger JR, Wu G, Endicott TJ, Mehta M, Curran W, Phan SC. Results of the Phase I Dose-Escalating Study of Motexafin Gadolinium with Standard Radiotherapy in Patients with Glioblastoma Multiforme. Int J Radiat Oncol Biol Phys. 2007 Jun 7; (2007). 5. Hebb MO, McArthur DL, Alger J, Etchepare M, Glenn TC, Bergsneider M, Martin N, Vespa PM. Impaired percent alpha variability on continuous electroencephalography is associated with thalamic injury and predicts poor long-term outcome after human traumatic brain injury. J Neurotrauma. 24(4):579-90 (2007). 6. Bang OY, Saver JL, Buck BH, Alger JR, Starkman S, Ovbiagele B, Kim D, Jahan R, Duckwiler GR, Yoon SR, Vinuela F, Liebeskind DS. Impact of collateral flow on tissue fate in acute ischemic stroke. J Neurol Neurosurg Psychiatry. 2007 Dec 20; (2007). 7. Ovbiagele B, Saver JL, Sanossian N, Salamon N, Villablanca P, Alger JR, Razinia T, Kim D, Liebeskind DS. Predictors of Cerebral Microbleeds in Acute Ischemic Stroke and TIA Patients. Cerebrovasc Dis. 22(5-6):378-383 (2006). 8. Ovbiagele B, Saver JL, Sanossian N, Salamon N, Villablanca P, Alger JR, Razinia T, Kim D, Liebeskind DS. Predictors of cerebral microbleeds in acute ischemic stroke and TIA patients. Cerebrovasc Dis. 22(5-6):378-83 (2006). 9. Kidwell CS, Alger JR, Saver JL. Evolving paradigms in neuroimaging of the ischemic penumbra. Stroke. 35(11 Suppl 1):2662-5 (2004). 10. Kidwell CS, Chalela JA, Saver JL, Starkman S, Hill MD, Demchuk AM, Butman JA, Patronas N, Alger JR, Latour LL, Luby ML, Baird AE, Leary MC, Tremwel M, Ovbiagele B, Fredieu A, Suzuki S, Villablanca JP, Davis S, Dunn B, Todd JW, Ezzeddi. Comparison of MRI and CT for detection of acute intracerebral hemorrhage. JAMA. 292(15):1823-30 (2004). 11. Vespa P, McArthur DL, Alger J, O'Phelan K, Hattori N, Wu C, Glenn T, Bergsneider M, Martin NA, Hovda DA. Regional heterogeneity of post-traumatic brain metabolism as studied by microdialysis, magnetic resonance spectroscopy and positron emission tomography. Brain Pathol. 14(2):210-4 (2004). 12. Fiehler J, Knudsen K, Kucinski T, Kidwell CS, Alger JR, Thomalla G, Eckert B, Wittkugel O, Weiller C, Zeumer H, Rother J. Predictors of apparent diffusion coefficient normalization in stroke patients. Stroke. 35(2):514-9 (2004). 13. Ostrem JL, Saver JL, Alger JR, Starkman S, Leary MC, Duckwiler G, Jahan R, Vespa P, Villablanca JP, Gobin YP, Vinuela F, Kidwell CS. Acute basilar artery occlusion: diffusion-perfusion MRI characterization of tissue salvage in patients receiving intra-arterial stroke therapies. Stroke. 35(2):e30-4 (2004). 14. Levitt JG, O'Neill J, Blanton RE, Smalley S, Fadale D, McCracken JT, Guthrie D, Toga AW, Alger JR. Proton magnetic resonance spectroscopic imaging of the brain in childhood autism. Biol Psychiatry. 54(12):1355-66 (2003). 15. Kidwell CS, Alger JR, Saver JL. Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging. Stroke. 34(11):2729-35 (2003). 16. Shih LC, Saver JL, Alger JR, Starkman S, Leary MC, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Villablanca JP, Vespa PM, Kidwell CS. Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue. Stroke. 34(6):1425-30 (2003). 17. Kidwell CS, Saver JL, Villablanca JP, Duckwiler G, Fredieu A, Gough K, Leary MC, Starkman S, Gobin YP, Jahan R, Vespa P, Liebeskind DS, Alger JR, Vinuela F. Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke. 33(1):95-8 (2002). 18. Kidwell CS, Saver JL, Starkman S, Duckwiler G, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Gobin YP, Vinuela F, Alger JR. Late secondary ischemic injury in patients receiving intraarterial thrombolysis. Ann Neurol. 52(6):698-703 (2002). 19. Alger JR, Frew AJ, Cloughesy TF, Del Vecchio W, Villablanca JP, Curran JG. Novel methodology for the archiving and interactive reading of clinical magnetic resonance spectroscopic imaging. Magn Reson Med. 48(3):411-8 (2002). 20. Haney S, Thompson PM, Cloughesy TF, Alger JR, Toga AW. Tracking tumor growth rates in patients with malignant gliomas. A test of two algorithms. AJNR. American Journal of Neuroradiology. 22:73-82 (2001). 21. Haney S, Thompson PM, Cloughesy TF, Alger JR, Frew A., Torres-Trejo A., Mazziotta JC, Toga, AW. Tracking tumor growth rates in patients with malignant gliomas. A test of two algorithms. Journal of Computer Assisted Tomography. 25:529-36 (2001). 22. Haney SM, Thompson PM, Cloughesy TF, Alger JR, Torres-Trejo A, Mazziotta JC, Toga AW. Mapping therapeutic response in a patient with malignant glioma. Journal of Computer Assisted Tomography. 25(4): 529-36 (2001). 23. Kidwell CS, Saver JL, Mattiello J, Warach S, Liebeskind DS, Starkman S, Vespa P, Vinuela F, Villablanca JP, Martin NA, Frazee J, Alger JR. Diffusion-perfusion MR evaluation of perihematomal injury in hyperacute intracerebral hemorrhage. Neurology. 57:1611-1617. (2001). 24. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Woods RP, Alger JR. Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans. Neurology. 57:2015-2021 (2001). 25. Kidwell CS, Saver JL, Villablanca JP, Duckwiler G, Fredieu A, Gough K, Leary MC, Starkman S, Gobin YP, Jahan R, Vespa P, Liebeskind DS, Alger JR, Vinuela F. MRI detection of microbleeds prior to thrombolysis: an emerging application. Stroke. 33:95-98 (2001). 26. Kidwell CS, Saver JL, Mattiello J, Warach S, Liebeskind DS, Starkman S, Vespa P, Vinuela F, Villablanca JP, Martin NA, Frazee J, Alger JR. Diffusion-perfusion MR evaluation of perihematomal injury in hyperacute intracerebral hemorrhage. Neurology. 57:1611-1617 (2001). 27. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Woods RP, Alger JR. Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans. Neurology. 57:2015-2021 (2001). 28. Kidwell CS, Saver JL, Mattielo J, Warach S, Liebeskind D, Starkman S, Vespa PM, Martin NA, Villablanca JP, Frazee J, Alger JR. Diffusion-perfusion MRI evaluation of perihematomal injury in hyperacute intracerebral hemorrhage. Neurology. 57:1611-1617 (2001). 29. Lee L, Kidwell C, Alger JR, Starkman S, Saver JL. Impact upon stroke subtype diagnosis of early diffusion weighted MRI and MR angiography. Stroke. 31:1081-1089 (2000). 30. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Kalafut M, Alger JR. Thrombolytic Reversal of Acute Human Cerebral Ischemic Injury shown by Diffusion/Perfusion Magnetic Resonance Imaging. Annals of Neurology. 47:462-9 (2000). 31. Harper RM, Bandler R, Spriggs D, Alger JR. Lateralized and widespread brain activation during transient blood pressure elevation revealed by magnetic resonance imaging. Journal of Comparative Neurology. 417:195-204 (2000). 32. Gupta RK, Cloughesy TF , Sinha U, Garakian J, Lazareff J, Rubino G, Rubino L, Becker DP, Vinters HV, Alger JR. Glioma MRS, Diffusion MRI and Histology: Choline and ADC Correlate with Cell Density. Journal of Neuro-oncology. 50:215-226 (2000). 33. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin P, Jahan R, Vespa P, Kalafut M, Alger JR. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Annals of Neurology. 47:462-469 (2000). 34. Lee U, Kidwell CS, Alger JR, Starkman S, Saver JL. Impact on stroke subtype diagnosis of early diffusion-weighted magnetic resonance imaging and magnetic resonance angiography. Stroke. 31:1081-1089 (2000). 35. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin P, Jahan R Vespa P, Kalafut M, Alger JR. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Annals of Neurology. 47:462-469 (2000). 36. Lee U, Kidwell, Alger JR, Starkman S, Saver JL. Impact on stroke subtype diagnosis of early diffusion-weighted magnetic resonance imaging and magnetic resonance angiography. Stroke. 31:1081-1089 (2000). |
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